雪原医生

职业经历：雪原、医学博士、主任医师、教授、博士生导师。天津市首届名医。总医院外科二总支书记。1990年至今，在天津医科大学总医院骨科工作。1996-1997年在日本神户大学骨科临床进修。30年安全医疗。擅长诊治颈胸椎管狭窄、退变、创伤、畸形、炎症、肿瘤等各种脊柱疾病和肩关节疾病。主要从事颈、胸椎疾病、骨质疏松、手术机器人的感知方法研究。以课题负责人获得国家自然科学基金6项，以课题组第2名获得国家自然科学基金2项，以第1完成人获天津市科技进步2等奖1项，以第2完成人完成国家863手术机器人课题1项。通讯作者在SCI发表论文50余篇。在北美和亚太颈椎年会大会发言宣读论文多篇，在日本脊柱年会大会宣读论文多篇，在国际骨科年会宣读论文。社会任职：中国医师协会骨科医师分会颈椎学组委员，中国医师协会骨科医师分会继续教育学组委员。中国医师协会老年医学会委员。北美脊柱外科学会（NASS)会员。中华医学会天津创伤分会副主任委员，中华医学会天津运动医学分会副主任委员。中华医学会结核病分会华北地区委员会副主任委员。国家卫健委留学生师资培训基地讲师。以通讯作者或第一作者发表SCI论文：1.Functional Connectivity Changes of the Visual Cortex in the Cervical Spondylotic Myelopathy Patients: A Resting-State fMRI Study.Chen Z, Zhao R, Wang Q, Yu C, Li F, Liang M, Zong Y, Zhao Y, Xiong W, Su Z, Xue Y.Spine. 2019 Sep 10. 2.0.5 - 1 Fold Intervertebral Distraction is a Protective Factor for Adjacent Segment Degeneration in Single-Level Anterior Cervical Discectomy and Fusion.Xiong W, Zhou J, Sun C, Chen Z, Guo X, Huo X, Liu S, Li J, Xue Y.Spine. 2019 Aug 16. 3.Incidence of Surgical Site Infection After Spine Surgery: A Systematic Review and Meta-Analysis.Zhou J, Wang R, Huo X, Xiong W, Kang L, Xue Y.Spine. 2019 Aug 27.4.A Transcriptome-Level Study Identifies Changing Expression Profiles for Ossification of the Ligamentum Flavum of the Spine.Han Y, Hong Y, Li L, Li T, Zhang Z, Wang J, Xia H, Tang Y, Shi Z, Han X, Chen T, Liu Q, Zhang M, Zhang K, Hong W, Xue Y.Mol Ther Nucleic Acids. 2018 Sep 7. 5.miR-342-3p promotes osteogenic differentiation via targeting ATF3.Han Y, Zhang K, Hong Y, Wang J, Liu Q, Zhang Z, Xia H, Tang Y, Li T, Li L, Xue Y, Hong W.FEBS Lett. 2018 Dec 6.Disc associating axial pain were indicated by PLL resection in ACDF surgery.Lin W, Xue Y, Zhao Y, Zong Y, Sun C, Pei B, Wang P.Eur Spine J. 2017 Apr. 7.Depression is associated with increased incidence of osteoporotic thoracolumbar fracture in postmenopausal women: a prospective study.Zong Y, Tang Y, Xue Y, Ding H, Li Z, He D, Zhao Y, Wang P.Eur Spine J. 2016 Nov 8.Extensive laminectomy for multilevel cervical stenosis with ligamentum flavum hypertrophy: more than 10 years follow-up.Li Z, Xue Y, He D, Tang Y, Ding H, Wang Y, Zong Y, Zhao Y.Eur Spine J. 2015 Aug 9.The CT and intraoperative observation of pedicel-ossification tunnel in 151 cases of thoracic spinal stenosis from ossification of ligamentum flavum.Zhao Y, Xue Y, Shi N, Zong Y, Yang Z, He D, Wang Y, Ding H, Li Z, Tang Y.Eur Spine J. 2014 Jun 10.Aggravation of spinal cord compromise following new osteoporotic vertebral compression fracture prevented by teriparatide in patients with surgical contraindicationsZhao Y, Xue R, Shi N, Xue Y, Zong Y, Lin W, Pei B, Sun C, Fan R, Jiang Y. Osteoporos Int. 2016 Nov 11.Foot drop caused by single-level disc protrusion between T10 and L1.Zhang C, Xue Y, Wang P, Yang Z, Dai Q, Zhou HF.Spine. 2013 Dec 15 12.Visual cortex neural activity alteration in cervical spondylotic myelopathy patients: a resting-state fMRI study.Chen Z, Wang Q, Liang M, Zhao R, Zhu J, Xiong W, Su Z, Yu C, Xue Y.Neuroradiology. 2018 Jul 31. 13.Stratification of venous thromboembolism risk in burn patients by Caprini score.Li Q, Ba T, Wang LF, Chen Q, Li F, Xue Y.Burns. 2019 Feb 14.Could Teriparatide Replace Percutaneous Vertebral Augmentation for Patients with Osteoporotic Vertebral Compression Fracture to Some Extent? Zhou J, Xue Y.Clin Interv Aging. 2019 Dec 2 IF = 2.58515.Preoperative Modic changes are related to axial symptoms after anterior cervical discectomy and fusion.Zhou J, Li L, Li T, Xue Y.J Pain Res. 2018 Oct 26 16.Clinical efficacy of calcitonin compared to diclofenac sodium in chronic nonspecific low back pain with type I Modic changes: a retrospective study.Zhou J, Li T, Li L, Xue Y.J Pain Res. 2018 Jul 17 17.The analgesic effect of intravenous methylprednisolone on acute neuropathic pain with allodynia due to central cord syndrome: a retrospective study.Li L, Han Y, Li T, Zhou J, Sun C, Xue Y.J Pain Res. 2018 Jun 25 18.Drilling Condition Identification Based on Sound Pressure Signal in Anterior Cervical Discectomy Surgery.Shao F, Tang M, Bai H, Xue Y, Dai Y, Zhang J.Med Sci Monit. 2019 Sep 2 19.Biomechanical Effect of Different Graft Heights on Adjacent Segment and Graft Segment Following C4/C5 Anterior Cervical Discectomy and Fusion: A Finite Element Analysis.Zhang Y, Zhou J, Guo X, Cai Z, Liu H, Xue Y.Med Sci Monit. 2019 Jun 4 20.Effects of Intermittent Parathyroid Hormone 1-34 Administration on Circulating Mesenchymal Stem Cells in Postmenopausal Osteoporotic Women.Tang Y, Xia H, Kang L, Sun Q, Su Z, Hao C, Xue Y.Med Sci Monit. 2019 Jan 8 21.Tissue discrimination by bioelectrical impedance during PLL resection in anterior decompression surgery for treatment of cervical spondylotic myelopathy.Shao F, Bai H, Tang M, Xue Y, Dai Y, Zhang J.J Orthop Surg Res. 2019 Nov 6 22.Circumferential Decompression via a ModifiedCostotransversectomy Approach for the Treatment of Single Level Hard Herniated Disc between T10 -L1.Pei B, Sun C, Xue R, Xue Y, Zhao Y, Zong YQ, Lin W, Wang P.Orthop Surg. 2016 Feb 23.Treatment of Atypical Central Cord Injury Without Fracture or Dislocation.Wang Y, Xue Y, Zong Y, Ding H, Li Z, He D, Tang Y, Zhao Y, Wang P.Orthopedics. 2015 Jun 24.Effect of depression on femoral head avascular necrosis from femoral neck fracture in patients younger than 60 years.He D, Xue Y, Li Z, Tang Y, Ding H, Yang Z, Zhang C, Zhou H, Zhao Y, Zong Y. Orthopedics. 2014 Mar 25.Depression contributed an unsatisfactory surgery outcome among the posterior decompression of the cervical spondylotic myelopathy patients: a prospective clinical study.Zong Y, Xue Y, Zhao Y, Ding H, He D, Li Z, Tang Y, Wang Y.Neurol Sci. 2014 Sep 26.Laminoplasty and laminectomy hybrid decompression for the treatment of cervical spondylotic myelopathy with hypertrophic ligamentum flavum: a retrospective study.Ding H, Xue Y, Tang Y, He D, Li Z, Zhao Y, Zong Y, Wang Y, Wang P.PLoS One. 2014 Apr 16 27.A report on the prevalence of depression and anxiety in patients with frozen shoulder and their relations to disease status.Ding H, Tang Y, Xue Y, Yang Z, Li Z, He D, Zhao Y, Zong Y.Psychol Health Med. 2014 28.Regulation of the levels of Smad1 and Smad5 in MC3T3-E1 cells by Icariine in vitro.Zhou H, Wang S, Xue Y, Shi N.Mol Med Rep. 2014 Feb 29.Upper facet joint en bloc resection for the treatment of thoracic myelopathy caused by ossification of the ligamentum flavum.Yang Z, Xue Y, Dai Q, Zhang C, Zhou HF, Pan JF, Sheng D.J Neurosurg Spine. 2013 Jul 30.Surgical treatment of ossification of the ligamentum flavum associated with dural ossification in the thoracic spine.Yang Z, Xue Y, Zhang C, Dai Q, Zhou H.J Clin Neurosci. 2013 Feb 31.A new candidate substrate for cell-matrix adhesion study: the acellular human amniotic matrix.Guo Q, Lu X, Xue Y, Zheng H, Zhao X, Zhao H.J Biomed Biotechnol. 2012 32.Extensive laminectomy for the treatment of ossification of the posterior longitudinal ligament in the cervical spine.Zhao X, Xue Y, Pan F, Zhao H, Li P, Wang P, Ma X.Arch Orthop Trauma Surg. 2012 Feb 33.MicroRNA-375 as a potential serum biomarker for the diagnosis, prognosis, and chemosensitivity prediction of osteosarcoma.Liu W, Zhao X, Zhang YJ, Fang GW, Xue Y.J Int Med Res. 2018 Mar 34.Which vertebrae should be assessed in diagnosing osteoporosis by plain radiography? Comparative study of radiographic findings and bone mineral density measured by dual energy X-ray absorptiometry.Yuan X, Takahashi N, Terashita T, Nakatani M, Mizuno K.J Orthop Sci. 1998 IF?以课题负责人承担国家自然科学基金6项：1. 老年黄韧带骨化症中过表达的lncRNA-SNHG4成骨分子网络及应用探究，2019/01-2022/12，国家自然科学基金面上项目 2. 老年黄韧带骨化症软骨细胞miR24成骨相关的分子网络及机制探究，2015/01-2018/12，国家自然科学基金面上项目 3. 利用brainbow研究Foxp1基因在小鼠C5神经根损伤后短固有束重塑过程中的作用，2013/01-2013/12，国家自然科学基金面上项目4. 3D粘附下DISH黄韧带骨化细胞的成骨相关性miRNA分析，2010/01-2010/12，国家自然科学基金面上项目 5. 自然衍发基质与构建表达矩阵预言成骨miRNAs的研究，2008/01-2010/12，国家自然科学基金面上项目6. 自然衍发基质运载Spemann期信息MSCs投递偶联因子防治PMOP骨折的研究，2006/01-2006/12，国家自然科学基金面上项目以第2完成人承担863计划子课题一项：1. 基于CT图像导航的脊柱微创手术机器人系统，国家高技术研究发展计划（863计划），课题组副组长以第1完成人获天津市科技进步二等奖1项：1. 根黄通道的发现及其临床意义，天津市科技进步二等奖，第1完成人