曹强医生

曹强，男，副主任医师，医学博士，擅长肾癌、膀胱癌、前列腺癌以及前列腺增生，肾上腺肿瘤等疾病的诊断与微创治疗。专业研究方向为肾癌的基础和临床研究，在本专业领域发表学术论文十余篇。目前参与国家自然科学基金项目两项。【科研项目】1. 国家自然科学基金项目：mTOR 信号通路基因遗传变异与肾癌发病和耐药机制的研究主要参与者。2. 国家青年科学基金项目：MicroRNA-34b/c 基因启动子区多态性及其甲基化与肾癌遗传易感性及其机制研究主要参与者。【代表文章】1. Cao Q, Qin C, Ju X, Meng X, Wang M, Zhu J, Li P, Chen J, Zhang Z, Yin C. Chromosome 11q13.3 variant modifies renal cell cancer risk in a Chinese population. Mutagenesis, 2012 May; 27(3):345-50. 2. Cao Q, Ju X, Li P, Meng X, Shao P, Cai H, Wang M, Zhang Z, Qin C, Yin C. A functional variant in the MTOR promoter modulates its expression and is associated with renal cell cancer risk. PLoS One, 2012; 7(11):e50302.3. Cao Q, Qin C, Meng X, Ju X, Ding Q, Wang M, Zhu J, Wang W, Li P, Chen J, Zhang Z, Yin C. Genetic polymorphisms in APE1 are associated with renal cell carcinoma risk in a Chinese population. Mol Carcinog, 2011 Nov; 50(11):863-70.4. Cao Q, Qian M, Wang XF, Wang B, Wu HW, Zhu XJ, Wang YW, Guo J. Negative feedback regulation of Raf/MEK/ERK cascade after sublethal cerebral ischemia in the rat hippocampus. Neurochem Res, 2011 Jan; 36(1):153-62. 5. Qin C, Cao Q, Ju X, Wang M, Meng X, Zhu J, Yan F, Li P, Ding Q, Chen J, Gu M, Zhang W, Yin C, Zhang Z. The polymorphisms in the VHL and HIF1A genes are associated with the prognosis but not the development of renal cell carcinoma. Ann Oncol. 2012 Apr; 23(4):981-9.6. Qin C, Cao Q, Li P, Ju X, Wang M, Chen J, Wu Y, Meng X, Zhu J, Zhang Z, Lu Q, Yin C. Functional promoter -31G>C variant in survivin gene is associated with risk and progression of renal cell cancer in a Chinese population. PLoS One, 2012; 7(1):e28829.7. Chen J, Cao Q, Qin C, Shao P, Wu Y, Wang M, Zhang Z, Yin C. GPx-1 polymorphism (rs1050450) contributes to tumor susceptibility: evidence from meta-analysis. J Cancer Res Clin Oncol, 2011 Oct; 137(10):1553-61.8. Zhang L, Mi Y, Cao Q, Wang W, Qin C, Wei J, Zhou Y, Li Y, Tang M, Liu W, Zhang W, Zou J. Update analysis of studies on the MMP-9 -1562 C>T polymorphism and cancer risk. Mol Biol Rep, 2012 Apr; 39(4):3435-41.9. Chen J, Shao P, Cao Q, Li P, Li J, Cai H, Zhu J, Wang M, Zhang Z, Qin C, Yin C. Genetic variations in a PTEN/AKT/mTOR axis and prostate cancer risk in a Chinese population. PLoS One, 2012; 7(7):e40817.10. Li P, Cao Q, Shao PF, Cai HZ, Zhou H, Chen JW, Qin C, Zhang ZD, Ju XB, Yin CJ. Genetic polymorphisms in HIF1A are associated with prostate cancer risk in a Chinese population. Asian J Androl, 2012 Nov; 14(6):864-9.11. Wang S, Cao Q, Wang X, Li B, Tang M, Yuan W, Fang J, Qian J, Qin C, Zhang W. PAI-1 4G/5G Polymorphism Contributes to Cancer Susceptibility: Evidence from Meta-Analysis. PLoS One. 2013;8(2):e56797.